buy vantin cheap prescription periactin buy amaryl mg buy fincar online uk tofranil dosage instructions what is allegra d 24 hour used for metformin hydrochloride tablets ip 500 mg side effects viagra jelly wikipedia what is minocin prescribed for ordering skelaxin does toradol come in pills cialis tadalafil comprare where can i purchase purim where can i buy biaxin online without a prescription buy retin a cream uk purchase forzest can you get high from ranitidine methotrexate without prescription miami levothyroxine vs synthroid side effects how to use advair diskus 500/50 price for zofran generic premier league player stats assists information on fluoxetine medication cephalexin medication order donde puedo comprar metformina en venezuela generic moduretic us xenical shipping overseas best generic evista review where to plant amaryllis glucophage lowest price almased turbo diet forum buy mestinon online overnight flovent coupon printable doxazosin roche precio argentina acheter furosemide en ligne non prescription acyclovir for sale where to buy periactin online uk what is carafate drug class hydrocortisone acetate cream atorlip-10 australia price flagyl pills cats pharmacies canada vpxl perscription deltasone dosage recommended viagra medicine name like viagra pill face other guys lanoxin by mail order how to use diamox to prevent altitude sickness order avodart from mexico without prescription sinemet how to buy order non generic digoxin diclofenac gel no prescription needed levitra brand for sale bupropion hcl sr coupons biaxin xl 500mg clarithromycin what is it used for cephalexin 5mg tablets lipitor on line in the usa online vermox with no prescription genuine bentyl buy drugs methylprednisolone dosage dogs ortho tri cyclen acne better liv 52 online ordering best generic trazodone sites generic viagra jelly buy canada generic name for adalat xl depakote drug wiki keppra for men sale in uk vpxl sold over counter buy sinequanone online atenolol dosage forms artane for daily use canada nimotop order canada canada order tretinoin 0,05 generic prednisolone acetate eye drops arjuna without prescription cefixime gonorrhea pharyngitis oxytrol prescription coupon cytotec mail order buy voltaren online india depo provera reviews side effects topamax generic pill identifier prescription drugs with no prescription needed overnight erection packs 1 drugs online brand vermox for sale where can i order finax alli pharmacy mail order nizagara tablets side effects haldol 20 mg buy benemid uk is there a natural viagra what is shallaki used for can you get high from hydrochlorothiazide how to purchase viagra plus online buspar generic release date generic tamoxifen usa pharmacy purchase micronase cheap antivert generic release date buy amitriptyline without generic order trial erection packs 3 online united support services bedford va tretinoin 0,025 pharmacy order buy parlodel online overnight generic celebrex alternatives celebrex xl pharmacy coupon what happens when you overdose on anti anxiety pills cipla share price india buy ophthacare mexico coupon buy hyzaar alli pill buy what does the yasmin pill do suppliers of confido in us buy clavamox cats no prescription med cab brand cialis hydrea to buy from europe ginseng spa massage salem ct buying lithium from canada no prescription pregnancy success stories using clomid levitra super active side effects uk ketoconazole shampoo boots que es el omifin para hombres citalopram hydrobromide renagel tablets used salzarex over the counter toradol buy sarafem online overnight anafranil from europe buy ditropan singapore average price of accutane without insurance fincar reviews for men pharmacy online no prescription cephalexin to buy levitra professional in uk free morning after pill bristol what does chloroquine renagel on line purchase remeron online order hoodia pills amazon allopurinol tablets 100 mg amoxil generic release date is singulair generic now buy retin-a ge online canadian online pharmacy for aricept nike air max 1 leopard mens what are the side effects of effexor xr metformin 500 mg price cvs cheapest levitra professional paypal buy nizoral pills in the india purchase voltaren in canada how long do side effects of celexa withdrawal last lamisil side effects anxiety buy aldactone pfizer medication get online prescription diflucan delivery buy motilium 80 mg online procardia tablets uk list of tesco stores selling geriforte syrup alli 10.00 coupon cialis professional 5mg what is viagra prescribed for cialis 5 mg dosage buy aspirin boots where to buy alesse online usa metronidazole where to buy buy estrace online from usa skelaxin tablets interactions cheap genuine naprosyn online buy plavix canada pharmacy zofran odt generic cost cipro shelf life algodones pharmacy prices vasotec discount how much does generic lipitor cost without insurance prescription diflucan side effects are alligators endangered in florida diclofenac gel in the uk evecare next day shipping diovan 100mg tablet canadian prescriptions acheter du clomid sans ordonnance what is zyrtec d used for cheap famvir 40 mg zyrtec d cost computer rx pharmacy software oklahoma city buy lady era online india what is diclofenac potassium used for list of tesco stores selling sominex coversyl arginine 10mg side effects generic prinivil switzerland generic metformin online in us buy risperdal risperidone indian allies of the french were maximum daily dose of sinemet what is cardizem prescribed for testosterone cream men application non prescription actonel pharmacy hytrin medicine online blue pill mylan a1 xanax can keflex cause weight gain generic cephalexin overnite shipping myambutol brand positioning clomid and serophene cost amitriptyline without a prescription from canada best generic chloroquine sites is singulair now generic avapro hct side effects finax tablets uk how to order revia citalopram 20 mg get you high betnovate cream over counter buy strattera from canada vpxl perth australia finax price india side effects eltroxin 25mcg tablets danazol without prescription miami yasmin echeck metoclopramide 10 mg prospect orlistat pills ebay can i make nitrofurantoin cipro flagyl combination side effects diovan without a prescription zithromax canadian pharmacy buy generic proventil order diovan 120 mg singulair rxlist where can i buy acai berry juice in the philippines canadian pharmacy without rx grifulvin v tablets for sale cheap remeron usa inhouse pharmacy discount coupon comprar amantadine original zanaflex tizanidine allopurinol discounts etodolac spain suprax dose danazol for daily use canada viagra in sydney keflex overnight shipping cheap cheap advair mg ethionamide side effects uk buy procardia from mexico online cialis compare discount price is there any medication for anxiety over the counter arava lawsuit what is prazosin 2 mg used for adverse effects of hydrochlorothiazide esidrix best place to order celexa in us mexican pharmacy online phentermine lipothin max dose can you discount buy flovent online buy adalat 60 mg finasteride for cheap generic differin gel canada benadryl allergy 100 tablets over counter nitroglycerin ointment cheapest augmenting path algorithm suprax online pharmacy uk cost of singulair generic what are the side effects of zantac in children what is the cost of synthroid cost without insurance discount januvia from canada pcm pharmacy viagra best price for real rosuvastatin viagra naturale vendita online generic cardizem 180 mg cymbalta supplier in uk how to apply estrace cream protonix online in canada party pills for sale online generic name alphagan p list of indian journals in pharmacy mexican pharmacy no prescription aciclovir cleocin 75mg/5ml granules 100ml order medrol no prescription femcare maximum dosage can you get atorlip-20 cialis tadalafil 50 100 mg online cytoxan india cheapest acai tablets uk prevacid shortage buy differin online no prescription united states side effects of valtrex and alcohol topamax discounts codes clomid tablets reviews cialis health shop mup generic forzest buy canada motilium side effects in children torsemide uses medication acquisto zyloprim sicuro online finast canada overnight delivery can you buy chloroquine looking counter protonix mg usa nimotop results forum getting a viagra prescription online pamelor buy generic aristocort with bonus can you buy benadryl in japan cloridrato de ciprofloxacino + dexametasona prec,o zestril for sale hoodia gordonii onde comprar curitiba generic drug amaryl stopping depo provera injection do you need rx mentat social anxiety and depression bupropion price increase buy zoloft online legal risperdal m tab price ordering trimox here in canada keppra comprar brasil what is flovent drugs purchasing xenical online uk best price for hydrochlorothiazide lantus cheap canada pharmacy order revia cheap norvasc prices at costco where to buy orlistat in canada safely betnovate cheap cost of generic prozac without insurance trimix tables download dilaudid hydromorphone rectal side effects of cefixime in infants arthritis in feet exercises what kind of drug is carafate generic alesse no prescription buy lithium medication amoxil free shipping merck propecia coupon what class of drugs is mobic online ethionamide india is levothroid generic where can i order sominex unicure remedies private limited paroxetine generic cost discount viagra without rx plavix dosage instructions cipro dosage for uti treatment combivent asthma medication generic actos 300 mg generic serophene paypal cymbalta reviews weight gain buy cialis 200 where can i buy paroxetine purchase viagra germany propecia discount prices levlen on line no script buy genuine pariet uk buy levitra in arizona generic name for strattera over the counter equivalent to celexa cheap midamor no prescription buy cefixime 400 mg online abilify generic release date femara infertility twins can you buy cardura buying zoloft from canada no prescription what does prevacid do piracetam dosage for kids brazil and mexico allies cymbalta 20 mg vs 30 mg zebeta discounts codes long term side effects of retin-a 0,025 genuine hytrin best price allegra tablet sale canadian medication information sites norvasc echeck lipitor dosage side effects of long term use of erythromycin buy kamagra in bulk unisom tablets while pregnant viramune xr generic how to take emsam mg cleocin 40 mg dose Purchase tenormin 25 mg viagra over the counter boots many lozol usa sale liquid tadacip review how to use lasix for weight loss crestor buy levothroid 10 how fast does wellbutrin start working effexor xr generic available when medication viagra plus without a prescription anacin tablet india buy vermox for daily use any good reviews on cymbalta effexor xr 150 mg weight gain hydrochlorothiazide online in us lithium metal cost per gram buy hong kong diakof without pharmacy bactrim birth control online australia tadapox not generic herbal viagra does it work is generic remeron effective online lisinopril india chloroquine online pharmacy uk generic lariam in usa isoptin looking for ortho tri cyclen side effects libido can buy atorlip-10 online is imitrex over the counter how to buy femara in london can you only get azulfidine on prescription risperdal order on web indocin usa cvs prices where can i buy viagra in india buy indomethacin 50mg on line femara drug in mexico pharmacy imitrex tablets side effects crestor tablets buy kamagra oral jelly online pharmacy uk levaquin side effects in elderly propecia side effects men over 50 buy albendazole 400 mg online low cost arava cialis internationale generic metformin canada how long does it take for medrol dose pack to start working cost of levaquin antibiotic lexapro com savings card prescription male enhancement drugs aurochem laboratories review gasex dosage too high what is mometasone furoate ointment usp 0.1 india pharmacies online that sell lipitor generic ralista switzerland fluoxetine common dosage cafergot without prescriptions viagra sublingual tablets from buy where to diclofenac lowest priced famvir zoloft sales 2011 cheap prednisolone uk buy glucotrol xl astrailia online buy clonidine without diclofenac sodium side effects liver zyban shipping overseas generic for avodart 0.5 mg canada drugs synthroid with prescription celexa reviews for ocd reminyl online legally dipyridamole where to buy in canada indinavir coupons prednisone 40 mg at once can you buy hydroxychloroquine fast worldwide shipping celebrex canada companies only promethazine wikipedia generic zithromax safe trental price pain pills online rumalaya liniment buy canada best price generic plavix is mail order viagra super active safe treatment for e.d. can buy prednisolone online cheap levitra india purchasing amitriptyline online what is florinef ceftin without insurance recommended synthroid dosage lamisil looking for over counter pravachol what is stromectol made of best pharmacy to order feldene atacand 32 mg prices alli order by phone zyvox mail order what does the medicine cephalexin do lamictal next day delivery can you buy valtrex online counter what is the generic name for zyrtec buy tretinoin cream gel minomycin suppositories buy best place to buy serophene tetracycline 500mg for dogs rosuvastatin side effects long term use turkish pharmacy companies where can i purchase venlor get adderall rx online sildenafil citrate tablets caverta 3000 feldene australia viagra side effects vision prescribed non prescription luvox benadryl sold over counter florida maxalt xenical discount pharmacy buy cipro xr online chewable viagra mexico cyklokapron for sale australia comprar penegra portugal atorlip-5 overnight pharmacy dosage of ivermectin for horses rumalaya forte by mail propranolol beta blockers for anxiety amoxil no prescription canada discount femcare mg order generic dutas aciclovir australia companies only where to buy abilify online canada drugs where can you buy antabuse in canada singulair shoppers drug mart where can i get some propranolol new alli doesn;t work levothyroxine tablets and alcohol comprar wellbutrin sr original amoxicillin no prescription buy zofran odt canada reviews forum alli weight loss buyers of zaditor canada roxithromycin ordering online pharmacy cheap calan blanes holiday pharmacy online overdose synthroid symptoms is allopurinol over the counter drugs tadalis sx for sale uk pharmaceutical machinery januvia lawsuit 2012 what does the medication plavix do calan drug class kamagra pay with paypal uk dog medication without prescriptions hoodia prix en pharmacie en france periactin usage motilium hangover cure femara 2.5 mg 30 film tablet diflucan for purchase online forum view topic order periactin cymbalta medication uses cabergoline dostinex online buy kytril bulk is it legal to buy prescriptions from canada online buy levitra plus perth australia abilify without insurance prescription avandamet for sale philippines buy acticin online overnight what does robaxin make you feel like maximum daily dose of capoten nexium vs prilosec wiki lasix iv dosage can we trust cialis jelly online viagra nz buy medicine atarax syrup buy aldactone from india pros and cons of buying drugs from canada doxycycline monohydrate 100 mg dosage is diflucan legal in uk how to take erexin-v mg vytorin india plendil 10 mg pret decadron iv dose for nausea from where to buy viagra in pakistan acheter furosemide sans ordonnance cafergot delivery top best 1000 games generic viagra online pharmacy blog cialis brand name sale auk pharmaceutical sales jobs salary viagra overnight shipping cheap alphagan p drug cheap metformin tablets pharmacies diltiazem generic for healthy weight for 6 foot 3 man propecia results after 3 months motrin suppliers overseas periactin for itchy dogs strattera dosage recommended silver slimming tablets forum order propecia online no presctiption canadian robaxin tablet buy brand tenormin cheap hoodia uk proscar tablet sale buy nitroglycerin with no rx what does adalat xl do fertomid medication order xenical dosage directions which uk site to buy cafergot haldol decanoate shortage best site buy viagra uk tadalafil compare prices why is there a uk alli shortage xeloda without prescription miami finax australia anxiety medication for dogs side effects revista tu online 2011 kamagra uk boots buy nexium esomeprazole online xalatan for sale philippines buy tulasi bulk cheap lexapro sale uk colchicine buy online ireland pyridium 10 mg cost what is zyrtec tablets pharmacy has best price confido no rx lipothin online meclizine generic antivert ginseng order canadian lasix tablet abilify without insurance cost generic retino-a cream 0,025 safe reviews on aceon voltaren rx to otc switch best site to buy prevacid testosterone cream uk buy compare prices ciplox ordering benzaclin depo medrol onde comprar cozaar discount program maximum recommended dose of clomid suprax 400mg dosage rogaine 2 for sale australia how to buy cialis online in canada where is the love lyrics on screen cheapest erythromycin tablets uk online pharmacy voveran discount indocin mg which uk site to buy robaxin buying cyklokapron eritromicina gel styplon generic wikipedia drugs how to buy tamoxifen citrate cipro tablets used tretinoin uk buy viagra jellyfish what is the active ingredient in benzaclin diet pill alli uk diflucan in croatia cheap valtrex prescription buy orlistat online canada order blog eurax online what is haldol used for in hospice azithromycin buy online no prescription where can i get retino-a cream 0,05 pills atorlip-10 sold over counter meloxicam for dogs uk with new generic rivals lipitor;s sales halved viagra prescription cost atarax comprimidos embarazo viagra generic equivalent how long does it take to perform a liver biopsy aleve medicine reviews online doctor consultation prescription pain medication what does wellbutrin sr mean where to buy female cialis drugs online safe to buy generic aciphex from canada trimox medication online lopid pharmacy secure canadian pharmacy websites kamagra jelly paypal bezahlen mircette 50mg tablets missed buspar dose ventolin nebules information ordering propecia canada online retino ac gel for acne half price lanoxin methotrexate injection purchase buy silagra tablets online renova developments
Skip to content
Powikszanie czcionki Domylny rozmiar czcionki Pomiejszanie czcionki
Start arrow Zespoły neurologiczne arrow Zespół łamliwego chromosomu X

Menu główne



Zespół łamliwego chromosomu X Utwórz PDF Drukuj Wyślij znajomemu

Gen może wywoływać zespół chorobowy u młodych i starszych osób
Warszawa (PAP) - Gen odpowiedzialny za upośledzenie umysłowe dzieci z zespołem łamliwego chromosomu X jest związany z chorobą neurologiczną pojawiającą się u starszych mężczyzn - donieśli naukowcy za pośrednictwem serwisu "EurekAlert".

"Okazuje się, że jeden gen może powodować dwa zupełnie niezależne zespoły chorobowe, które dotykają dwie różne grupy wiekowe pacjentów" - mówi prowadzący badania prof. Paul Hagerman z Univeristy of California School of Medicine.

Jak tłumaczy badacz, odkryta niedawno u starszych mężczyzn choroba neurologiczna, która powoduje stopniowe niszczenie tkanki nerwowej mózgu i objawia się drgawkami, zaburzeniami równowagi i problemami z pamięcią, ma to samo podłoże genetyczne co zaburzenie rozwojowe o nazwie zespół łamliwego chromosomu X.

Przyczyną zespołu łamliwego chromosomu X i nowo opisanego schorzenia neurodegeneracyjnego są zmiany w genie FMR1 znajdującym się na chromosomie płciowym X. Nazwa zespołu łamliwego X wywodzi się od małego nietypowego przewężenia na tym chromosomie, które często pęka w trakcie przygotowywania chromosomów do analizy.

Zespół prof. Hagermana zaobserwował, że mężczyźni z chorobą mózgu powiązaną z wrażliwym chromosomem X mają liczne kuliste wtręty w komórkach nerwowych. Teraz naukowcy prowadzą dalsze badania, które mają wyjaśnić, z czego są złożone i z jakiego powodu powstają.

Według autorów, ta nowa odmiana degeneracji tkanki nerwowej może występować u jednego na 3 tys. mężczyzn. Dotychczas była opisywana jako "nietypowa choroba Parkinsona".

Jej objawy rozwijają się dopiero po 50. roku życia. Często mężczyźni nie zdają sobie sprawy, że są nosicielami zmiany genetycznej i przekonują się o tym dopiero, gdy zespół łamliwego X zostaje zdiagnozowany u wnuczka.

Naukowcy zaprezentowali swoje wyniki na dorocznym spotkaniu Amerykańskiej Akademii Neurologii w Honolulu.

Zespół łamliwego chromosomu X jest zaburzeniem rozwojowym, którego symptomy zaczynają pojawiać się w dzieciństwie. Jest to najczęściej występujące, po zespole Downa, upośledzenie umysłowe o podłożu genetycznym. Przyczyną są zmiany na chromosomie płciowym X, który u mężczyzn występuje tylko w jednej kopii. Oznacza to, że kobiety są najczęściej nosicielkami choroby, a przekazują ją synom. Ryzyko wystąpienia zespołu dotyczy jednego na 1,2 tys. mężczyzn i jedną na 2,5 tys. kobiet.

W 1991 roku odkryto, że przyczyną rozwoju choroby są zmiany w genie FMR1, którego funkcja nie została jeszcze dobrze poznana.

U mężczyzn schorzenie objawia się umiarkowanym lub silnym opóźnieniem rozwoju umysłowego, podczas gdy kobiety-nosicielki mogą przejawić najwyżej łagodne upośledzenie. Z kolei u niektórych mężczyzn z łamliwym X rozwój umysłowy może przebiegać zupełnie prawidłowo.

Osoby z zespołem łamliwego X mają wiele charakterystycznych cech fizycznych, jak odstające uszy, pociągłą twarz, duże jądra, płaskostopie i inne. Mają zaburzenia mowy, przejawiają też niektóre zachowania typowe dla osób z autyzmem, jak niewielki kontakt wzrokowy, mogą silnie gestykulować i mieć zaburzenia w odbiorze różnych bodźców zmysłowych. Objawy u chorych kobiet są zazwyczaj dużo mniej nasilone.



Ochrona Prawna


Zjazdy i seminaria