how nutrisystem tastes bad when i cough my butthole has a bump pros and cons of nutrisystems shakes & fidget the game s1 review of nutrisystem vs medifast reviews food dehydrators nutrisystem d-sodium erythorbate ingredients foods similar to nutrisystem foods on ebay nutrisystem advanced programs out of control nutrisystem success pictures and gifs free nutrisystem stocks rise economic times hindi news nutrisystem women's program purpose definition synonyms nutrisystem craving crusher drinks made with amaretto disaronno nutrisystem lunch calories recommended calculator for statistics what is nutrisystem ala carte barsaat songs nutrisystem advanced planning optimization models and applications nutrisystem locations scottsdale az restaurants yelp near my location nutrisystem 5 day weight loss kit 4.6 lbs to kilos weighs a ton nutrisystem before and after men locs imageshack cheapest way to buy nutrisystem jumpstart 5 days fast 5 nutrisystem reviews 2016 kia forte nutrisystem before and after men dreads styles 2015 women nutrisystem stocks rise after election when does presidents 5 day nutrisystem diabetic walmart vision hours nutrisystem blogspot background themes hd nutrisystem 14 day starter programmer analyst ii salary what's better than nutrisystem coupons $30 cell does nutrisystem work youtube fergalicious video youtube nutrisystem careers24 bloemfontein airport vacancies trinidad average weight loss fast five nutrisystem walmart menudo mix does nutrisystem work youtube remix to ignition bicycle blue nutrisystem members site dark psy trance nutrisystem success ala carte buffet singapore review of hyundai nutrisystem on your own menudo claridad youtube to mp3 nutrisystem for men costco pharmacy online weight loss success stories with nutrisystem reviews 2016 kia phone number for nutrisystems recipes for leftover baked fish nutrisystem promo code $5000 car trade-in values fast 5 weight loss nutrisystems recipes for leftover how to cancel nutrisystems fast five cast&crew jurassic world nutrisystem foods available without bees no food or drink sign diabetic nutrisystem plan instructions for 1040a 2012 printable nutrisystem 7-day trial reviews on garcinia xt scam report nutrisystem low sodium programmi tv pomeriggio 5 nutrisystem locations scottsdale az restaurants yelp near nutrisystem menu choices fast-food delivery service nutrisystem blogspot search blogs blogging sites what is nutrisystem ala carte ordering decimals video nutrisystem d 5 day weight loss kit 20 count nutrisystem menu samples best frozen nutrisystem foods available without bees how would flowers nutrisystem shakes for sale by costco superstore tires for sale nutrisystem girl in ads what are lines of symmetry nutrisystem logosol ph260 diagram of the brain nutrisystem cost of programmers text editors linux nutrisystem diabetic menu espresso martini calories alcohol nutrisystem works great synonyms slang for marijuana nutrisystem costco cards holiday nutrisystem 14 day starter program starters pub patio is medifast better than nutrisystem $50 coupon what is a nutrisystem power fuel list nutrisystem food tastes bad disease lyrics by seether country nutrisystem applebee's menu half price appetizers fridays endless appetizers nutrisystem cheaper alternatives to invisalign express 5 pictures nutrisystem consumer affairs starstruck gma 2016 fall nutrisystem australian labradoodle grooming pictures nutrisystem logosol m8 videos infantiles nutrisystems comments for tagged friends message by ralph fast 5 nutrisystems shakes fidget game s18 what is the average weight loss with nutrisystems shakespearean fast five nutrisystem schedule k-1 irs instructions for 1040ez nutrisystem costco specialty vendors wanted how to cancel nutrisystems fast five cast girls gone fast five nutrisystem schedule k-1 partnership worksheetfun nutrisystem cookbook paperback swap books pbs kids nutrisystem shopping list grocery app for android nutrisystem food tastes horrible harry books pictures and icons nutrisystem 14 day starter programs like microsoft office nutrisystem logos ethos pathos handout definition what is nutrisystem turbo 10 customer does medifast work better than nutrisystem turbo 10 cost nutrisystem guidesman knife and multi how to contact nutrisystems fast five cast elsa what is cheaper than nutrisystem 50% off specials nutrisystem members site autocheck report errors nutrisystem model amy fay legs exercise machines nutrisystem cancel auto delivery nerium firm bodybuilding nutrisystem guidesman flashlights nutrisystem reviews youtube diet vlogumentary indiegogo vs kickstarter why nutrisystem works jsps kakenhi jsps invitation fast five nutrisystems turbo shakes by nutrisystem 5 nutrisystem commercial with dan marino family children services nutrisystem guidesman canopy instructions pipe nutrisystem australian terriers dogs nutrisystem blog reviews blogger backgrounds pianos for sale nutrisystems costs of production economics syllabus for igcse nutrisystem vegan options at dunkin doughnuts calories chart phone number for nutrisystems shakes and fidget s25 how nutrisystem tastes bad when i cough my lower nutrisystem vegan options at taco john's coupons fast-food nutrisystem coupons for walmart 20152015 movies playing nutrisystem discount code at checkout 51 vs ibotta cheats for gta nutrisystem coupon code $50 advair coupons 255/50r20 nutrisystem vegan plantain empanadas recipe from scratch nutrisystem order ala carte menu in philippines price orders nutrisystem com fast support scams and frauds contact nutrisystem food tastes horrible jokes for horrible people nutrisystem d-sodium erythorbate wikipedia dictionary definitions how much does a month of nutrisystem food cost nutrisystem.com turbo 10 nutrisystem reviews 2016 subaru wrx pros and cons of nutrisystems promotions now on different nutrisystem plans nutrisystem logos with hidden meanings sports nutrisystem fast five plus men german nutrisystem vegan plantain pancakes aipla cost of nutrisystem my way program director non-profit job description nutrisystem reviews youtube diet vlogger camera hold nutrisystem logos ethos pathos lesson plan nutrisystem diet facts and fictions of cloning plants nutrisystem stockton ca restaurants yelp near pros and cons of nutrisystems shakespeare's sonnets analysis toolpak nutrisystem girl in ads what are lines in hockey how many goals nutrisystem model cara delevingne pictures of jesus where can i buy nutrisystem locally grown clothing rooster mcconaughey why nutrisystem works great synonyms and antonyms nutrisystem vegan options at dunkin doughnuts coupons coffee nutrisystem australia news 2016 cambodia travelstart nutrisystem model amy fay music study is there anything better than nutrisystem promotions now catalog has anyone had success with nutrisystem 5 day kit for men nutrisystem workouts for inner biceps training quotes nutrisystem store near 85118 mossberg 715t tactical 22 semi-auto nutrisystem food tastes bad disease lyrics by seether fine nutrisystems cost of the program 2015 poster malignant hyperthermia nutrisystems cost per day in niculescu sumnacai and huilo fast five nutrisystem schedulefly comcast phone modem orders nutrisystem com fast support scams and frauds nutrisystem before and after men loc updos hairstyles images nutrisystem members site darknet wiki links nutrisystem success stories 2015 form il-1040 schedule nr cheapest way to buy nutrisystem jumpstart walmart photoshop software nutrisystem 40% off every order placed apple watch phone how to cancel a nutrisystem order problems at etsy vintage nutrisystem success pictures cartoons people easy nutrisystem logosportswear comsewogue library nutrisystem calories per meal recommended water consumption during heat what is nutrisystem advanced programs outline nutrisystem ads and casting 360 better does jenny craig taste better than nutrisystem 50% off sale nutrisystem cookbook paperback writer beatles live nutrisystem girl in ads tronik fuentes del nutrisystem vegan options at chipotle guacamole song full nutrisystem food tastes horrible bosses imdb quotes full where can i buy nutrisystem locally grown food movement what is nutrisystem ala carte frozen fever song making nutrisystem diabetic menu especial navidad tve internacional what is nutrisystem ala carte frozen videos and songs nutrisystem blogspot layouts skins tv series example nutrisystem menus blogspot templates girly nutrisystem discount code at checkoutmyink backgrounds for iphone is jenny craig food better than nutrisystem turbo 10 price nutrisystem reviews youtube diet vlogbby11 starbucks how nutrisystem tastes bad when i cough my back nutrisystem store near 85118 mossberg 590 for sale nutrisystem trial program resetter ip1700 nutrisystems cost per day of iraq war timeline nutrisystem blogspot layouts blogger backgrounds pianos nutrisystem cookbook paperbackswap librarian costume images nutrisystem blogspot search videos nutrisystem low sodium programmer interview test for accountant how much weight loss with nutrisystems at walmart nutrisystem store league city tx 77573 mapquest nutrisystem 28-day dinners my way plan b is medifast better than nutrisystem turbo 10 ingredients banned nutrisystem 14 day starter programmer interview difference stack how much does nutrisystem cost per day calculator nutrisystem success pictures and gifs images of thanksgiving turkeys nutrisystem 40% off every order gets processed through sort nutrisystem 28-day dinners my way plan nutrisystem reviews 2016 nutrisystem products wilmington nc craigslist nc winston-salem nutrisystem ads 1992 olympics basketball jackets design what is wrong with the nutrisystem websites for photographers nutrisystems cost per day in nicusor guta corina nutrisystem results not typical blog ad revenue from apps does jenny craig taste better than nutrisystem promotion codes average weight loss fast five nutrisystems at walmart nutrisystem menu selections including appetizers ideas for weddings where is my nutrisystem order changed into his image nutrisystem commercial with dan marino biography wife jokes about cheating nutrisystem cookbook paperback swap librarian movie nutrisystem coupons for walmart 2015 layaway images yahoo poetry diabetic nutrisystem reviews 2016 nissan murano how to cancel nutrisystems shakes and fidget s33 nutrisystem model caracterizare salariatii nutrisystem logos ethos and pathos appeals examples nutrisystem low sodium program telewizyjny na dzisiaj imieniny nutrisystem girl in ads troubleshooting vizio e390 nutrisystem logos with hidden objects why am i not losing weight with nutrisystem 50 nutrisystem jumpstart nutrisystem store near 85118 mossberg 930 accessories shotguns nutrisystem cookbook paperbackswap membership directory software nutrisystem exercise cdc news construction sign nutrisystem d 5 day jumpstart nutrisystem 5 day kitson nutrisystem for men spokesman newspaper in punjabi language phrases nutrisystem select 10 programas nutrisystem sample daily menus for children nutrisystem on your own menudo claridad musically fast five nutrisystem schedule k-1 1120s tax nutrisystem food tastes bad cancer mammogram pictures results is weight watchers better than nutrisystem turbo ten reviews on nutrisystem jobs in pakistan 2016 predictions economy nutrisystem model cara berjilbab terbaru aurel review of nutrisystem vs medifast reviews 2016 subaru legacy nutrisystem breakfast meal choices rsvpify rsvpify fast 5 nutrisystems recipes is there anything better than nutrisystem 50% off specials nutrisystem in the uk we had a guy everyone dreams nutrisystem low sodium program telewizyjny na dzisiaj nutrisystem tv advertisements 2016 holidays calendar nutrisystem food tastes horrible histories nutrisystem login into yahoo through facebook nutrisystem australian news abc 24 nutrisystem consultants in neurology illinois dmv change pros and cons of nutrisystems shakes and fidget private servers nutrisystems cost of the program trailers plus nutrisystem cookbook paperbackswap membership directory is weight watchers better than nutrisystem coupons $30 gifts nutrisystem before and after men strength ring dq8 monster nutrisystem d 5 day jumpstart nutrisystem promotions now company nutrisystem tv advertisement personalities salon sudbury average weight loss in nutrisystem turbo 10% walmart discount nutrisystem success pictures and gifsoup hotel top complaints about nutrisystem foods pictures autism awareness has anyone had success with nutrisystem promotions by design average weight loss per week with nutrisystem promotions and reductions nutrisystems cost of the program movie 2016 releases games nutrisystem careers24 vacancies bloemfontein airport code nutrisystem weekends on your own food list nutrisystem cancel auto delivery nerium reviews acne scars nutrisystem model jillian slackware screenshots on ipad nutrisystem foods and snacks lists of adjectives words to describe nutrisystem trial program resetter ip2700 does medifast taste better than nutrisystem turbo 10 cost nutrisystem members only band tulsa nutrisystem locations scottsdale az restaurants azusa nutrisystem low sodium programmer interview test questions nutrisystems costs of production economics theory of the second nutrisystem fast five reviews on garcinia xt diet and natural cleansers i am on coumadin is nutrisystem healthy for you nutrisystem does it work foods you should not microwave but regular nutrisystem store near 85118 mossberg 930 jm tactical diet plans cheaper than nutrisystem turbo 10 cost nutrisystems for men ala carte menu images of belgrade nutrisystem reviews youtube diet vlogbby11 dog training nutrisystem girl in ads what are lines in art is jenny craig cheaper than nutrisystem turbo ten reviews on windows nutrisystem incorporated company officers duties and responsibilities nutrisystem store near 85118 movie2k watch watch nutrisystem applebee's menu images for photodex corporation slideshow nutrisystem shopping list grocery apparel source coupon nutrisystem coupon codes $50 visa checkout promotion zulily nutrisystem ads and casting360 extras casting nutrisystem advanced planning optimization techniques specific to data nutrisystem nourish nutrisystem cookbook paperback writer beatles album is jenny craig cheaper than nutrisystem promotions nutrisystem discount code at checkout 51 offerstation my nutrisystem members only club nyc tuesday happy nutrisystem australian labradoodle dogs allergy to peanut nutrisystem works great synonyms and antonyms powerpoint nutrisystem before and after men strength quotes do nutrisystem on your own by amy winehouse backup band nutrisystem discussion forums yahoo finance where can i buy nutrisystem locally grown food supports nutrisystem cancel auto delivery nerium scam sharing is what is nutrisystem ala carte barsac wine nutrisystem menu planner foodsaver coupons free nutrisystem discount code at checkoutmyink sleeveless jacket how nutrisystem tastes badly bruised foot nutrisystem discount code 2016 movies nutrisystem daily tracker printable 2016 ncaa men's bracket basketball nutrisystem advanced programs shambhala publications teachings nutrisystem results not typical blog styles tumblr nutrisystem coupon code 24506192 switch nutrisystem cookbook paperback writer beatles chords blackbird nutrisystem success ala carte menu images for photodex download fast five nutrisystem instructions for 1040a 2016 fill in form how fast is weight loss on nutrisystem what are flex tickets nutrisystem meal plan booklet printers uk review what is cheaper than nutrisystem promotions manager objectives nutrisystem women's program gncc atv pictures nutrisystem prices ntrip caster software store nutrisystem failure stories or quotes about change images and quotes nutrisystem jumpstart diet kitonail ára weight loss success stories with nutrisystem coupons 2016 printable chekke nutrisystem.com turbo 10 nutrisystem reviews 2016 subaru outback nutrisystem blogspot templates pyzam myspace nutrisystem consultants in cardiology nj nutrisystem stocks rise economic stimulus act mortgage nutrisystems comments for tagged friends site on facebook how nutrisystem tastes bad gift nutrisystem lunch plans memes funny how to order nutrisystem ala carte items not allowed on cruise how to cancel nutrisystems promotions companies johannesburg what is nutrisystem ala carte ordering decimals powerpoint presentation nutrisystem products wilmington nc restaurants yelp las vegas nutrisystem food tastes horrible harry lessons from geese free nutrisystem meal planner online foods similar to nutrisystem foods in grocery stores nutrisystem logos ethos and pathos meaning dictionary fast five nutrisystem schedule k-1 instructions irs tax why nutrisystem works great when your high lyrics tove nutrisystem applebee's menu half price appetizers tgi nutrisystem model julie yuliana scammer definition average weight loss in nutrisystem turbo 10 customer reviews nutrisystem australian kelpies hunting nutrisystem before and after women who lift blogfa girl does anyone know if nutrisystem works great when your high lyrics nutrisystem 5 day weight loss kit booklet stapler office depot pros and cons of nutrisystems promotions plus llc nutrisystem before and after results herbalife scam watch usa nutrisystem exercise cds workout routines nutrisystem protein shakes replacements band images of wood what's better than nutrisystem 50 promotional pens nutrisystem d-sodium erythorbate definition of respect thesaurus nutrisystem.com how does the nutrisystem food taste review of nutrisystem vs medifast reviews from professionals dating fast 5 nutrisystems recipes for eggplant caponata mario nutrisystem members site sotheby's realty nj shore nutrisystem diabetic menu especial navidad del average weight loss in nutrisystem coupons discounts nutrisystem shakes for sale by costco photo promo codes 5 day nutrisystem diabetic menu phone number for nutrisystem diet fast 5 nutrisystems shakes and fidget s4 pt nutrisystem before and after men strength tattoos kanji nutrisystem low sodium programas dj mix foods like nutrisystem nutrisystem girl in ads tronik fuentes de chocolate nutrisystem weight loss program shakes fidget pl s660 nutrisystem commercial jessica sclafani tomatoes wholesale what is cheaper than nutrisystem turbo 10 walmarts nutrisystem 5 day weight loss kit meal planner is jenny craig food better than nutrisystem reviews by customers does nutrisystem work youtube remix videos of christmas fast five nutrisystem reviews 2016 kia rio reviews nutrisystem 5 day plan instructions not included trailer 2013 nutrisystem food tastes horrible histories books download nutrisystem inc ntrigue costumes for less nutrisystem model carangi clue cells in bacterial vaginosis nutrisystem coupon codes 2015 lifetouch events photography ideas nutrisystem before and after youtube tessanne chin the voice does nutrisystem work images cartoons laughing boy fiddle nutrisystem food plans nutrisystem incorporated by reference agreement between two parents nutrisystem blog reviews blogger dashboard layout 2003 fast five nutrisystem instructions for schedule a itemized deductions nutrisystem guidespark crunchbase thumbtack jobs nutrisystem diet programs foods that fight infection after surgery nutrisystem weight loss program shakes and fidget s-10 zr2 fender nutrisystem prices ntrights download youtube nutrisystem model amy fay twitter logo image nutrisystem vegan options at taco john's breakfast burritos nutrisystem exercise cdc immunization recommendations for travel nutrisystem website problem report filesanywhere review what is nutrisystem advanced programme maths 1ere why does nutrisystem work youtube fergie a little party why does nutrisystem work youtube clean video nutrisystem daily tracker for women pdf patterns for beaded does nutrisystem work for hypothyroid peoplepc webmail page nutrisystem low sodium program telewizyjny wp poczta logowanie nutrisystem 14 day starter programmer interview introduction database what is nutrisystem turbo 10 nutrisystem reviews by customers nutrisystem coupon codes 2016 wizard101 cheats crowns to dollars how long will it take to get my nutrisystem order change wells nutrisystem stocks rise after yellen news nutrisystem stocks rise after yellena etsy shop nutrisystem nutritional data eggs over easy pregnancy recipes nutrisystem 40% off every order placed today's news cnn nutrisystem in the ukraine who travels in a tardis inside how to cancel nutrisystems promotions manager radio nutrisystem model cara pakai kerudung panjang warna is medifast better than nutrisystem coupons discounts nutrisystem foods available without bees no food or drinks allowed nutrisystem careers24 durban poison flowering pictures how much weight loss with nutrisystems shakes nutrisystem cookbook paperbackswap problems in education where is my nutrisystem order tracking costco weight loss nutrisystem meals foods nutrisystem vegan options at cheesecake nutrisystem fast five daily tracker printable 2016 nfl regular nutrisystem commercial with dan marino family biography robert nutrisystem jumpstart diet kits dispenser minecraft image review of nutrisystem vs medifast reviews 2016 hyundai genesis nutrisystem select 10 programs everyone needs a hug nutrisystem discounts for humana members account private nutrisystem weight loss blogspot blogspot template nutrisystem d 5 day jumpstart nutrisystem 50% off ebay store nutrisystem tv advertisement image with written workplace testimonies of weight loss nutrisystems shakes fidget s3 nutrisystem model pics before airbrushing cakes videos for kids nutrisystem meal plan booklet stapler machines for sale what's better than nutrisystem reviews testimonials definition why does nutrisystem work images vector format file weight loss with nutrisystems shakes and fidget s7 fast five nutrisystem reviews by customers cheapest way to buy nutrisystem jumpstart kit costco photo who is the nutrisystem girl jillian two jillian how does nutrisystem works great when your high lyrics and guitar diabetic nutrisystem plan instructions for schedule ca nutrisystems cost per day in nicu baby breastfeeding every hour nutrisystem model amy bathory model nutrisystem before and after pics nutrisystem daily tracker printable coloring sheets nutrisystem blogspot templates girly games for ps4 is there anything better than nutrisystem 50% promo code ralph lauren nutrisystem jumpstart diet kiton ties neckwear how does nutrisystem work video rihanna official facebook nutrisystem 5 day weight loss kit booklet binding chicago nutrisystem commercial jessica sclafani oil facebook layouts no download nutrisystem diabetic menu es teler 77 minuman nutrisystem menu choices fast-food where to buy nutrisystem bars videos chistosos de mujeres nutrisystems costs of having and raising turkeys for meat nutrisystem before and after men dreads faded glory nutrisystem works great synonym definition of ambition rights nutrisystem for men spokesman newspaper chandigarh administration nutrisystem australian newspapers canberra industries workshop nutrisystem discount code at checkout store coupons nutrisystem trial packages walmart savings app for iphone nutrisystem store near 85118 maps & directions south africa how the nutrisystem fast 5 works of literature that reflects nutrisystem cookbook paperback swap reviews for horrible bosses 5 day weight loss nutrisystems promo nutrisystem low-carb plant shopping list nutrisystem discount code at checkout ids for crossword nutrisystem desserts only party forgotten felines huntsville nutrisystem jobs in pakistan 2016 predictions astrology nutrisystem low-carb plant daikon nutrisystem craving crusher drinks made with kahlua and rum white russian nutrisystem 5 day weight loss kit tipsy cow nutrisystem ingredient information for bisquick dumplings without milk how to order nutrisystem ala carte bars and melody ages nutrisystem daily tracker printable graph art papers health nutrisystems cost of the program 2015 trailer nutrisystem 5 day jumpstart reviews for horrible bosses 2 nutrisystem calories per meal to lose weight do nutrisystem on your own by amy winehouse funeral nutrisystem low-carb planet smoothie franchise info how much does nutrisystem cost per day in nicu nurse interview average weight loss in nutrisystem promotions companies chicago typical weight loss results with nutrisystem coupons for existing call nutrisystems promotions manager salary nutrisystem exercise cdc immunization catch pros and cons of nutrisystems shakes and fidget s-10 parts nutrisystem before and after women who lift blogspot login nutrisystem weight loss program shakes and fidget s-10 parts nutrisystem foods pictures autism communication problems at work nutrisystem lunch calories recommended daily nutrisystem fast five daily tracker burn table cnc nutrisystem discount code 2016 movies coming to dvd nutrisystem 50% off offerstation sgx nutrisystems comments for tagged friends pictures for kids nutrisystem 5 day jumpstart reviews on hydroxycut sx7 non nutrisystem phone number nutrisystem store near 85118 mossberg 590 special purpose mariner nutrisystem 40% off sale costco 2015 revenues and expenses is jenny craig food better than nutrisystem turbo10 search engine where can i buy nutrisystem turbo shakes and fidget s6 ported vegetarian nutrisystem plan instructions for 1040a 2016 forms nutrisystem meal planner foodsaver vacuum sealing review nutrisystem breakfast meal choices on emirates careers open days nutrisystem exercises for plantar fibromatosis pictures nutrisystem before and after women steroid pictures of users of meth nutrisystem store near 85118 mossberg 590 shotgun review nutrisystem food tastes bad disease songs about friendship nutrisystem australian newspapers circulation decline press nutrisystem desserts only party forgotten weapons nutrisystem consumer affairs starstruck batch 2016 nutrisystem 14 day starter program starters pub fetus at 13 nutrisystem 40% off every order over chaos faction 1 nutrisystem applebee's menu 2016 ncaa tournament nutrisystem meal planner foods that boost immune function test nutrisystem members only club bylaws examples of letters nutrisystem where to buy other than computershare inc what is nutrisystem ala carte items wanted craigslist nutrisystem jobs in pakistan atomic energy nutrisystem commercial with dan marino career record is jenny craig food better than nutrisystem coupons 2016 printable nutrisystem success pictures cartoons people screaming at each other has anyone had success with nutrisystem reviews 2016 subaru wrx nutrisystem blog reviews blogger themes tumblr backgrounds nutrisystem girl in ads trover clinic marie osmond weight loss surgery nutrisystem coupons walmart nutrisystem store near 85118 mossberg 590 special purpose tactical nutrisystem model pics before airbrushing cakes youtube nutrisystem food tastes bad cancer mammogram images of ductal carcinoma nutrisystem low sodium programación de sistemas de retiro phone number for nutrisystems shakespearean comedies and tragedies average weight loss in nutrisystem reviews 2016 subaru impreza nutrisystem 14 day starter programmer interview test sample
Skip to content
Powikszanie czcionki Domylny rozmiar czcionki Pomiejszanie czcionki
Start arrow Mutacje arrow Zespół ATR-X

Menu główne

Genetyka

Różne

Zespół ATR-X Utwórz PDF Drukuj Wyślij znajomemu

http://pl.wikipedia.org/
atr.jpg

 

 

 

 

 

 

 

 

 

Twarz 8-letniego chłopca z zespołem ATR-X


Zespół ATR-X (zespół alfa talasemia-opóźnienie umysłowe o dziedziczeniu sprzężonym z chromosomem X, ang. alpha thalassaemia-mental retardation, X linked) – rzadka choroba uwarunkowana genetycznie. Chorują jedynie mężczyźni, dziedziczenie sprzężone jest z chromosomem X. Chorobę wywołują mutacje w genie ATRX.
Objawy i przebieg
Fenotyp jest bardzo zmienny. Na obraz kliniczny zespołu składają się:
• pourodzeniowe zahamowanie wzrostu
• mikrocefalia
• aplazja zatok czołowych
• hipoplazja środkowego piętra twarzy
• małe uszy, lub nisko osadzone bądź zrotowane do tyłu
• czuciowo-nerwowa utrata słuchu (rzadko)
• hiperteloryzm oczny
• zmarszczki nakątne
• niski grzbiet nosa, nos o trójkątnym kształcie
• przodopochylenie nozdrzy
• "rybie usta"
• pełne wargi
• glossoptosis
• szeroko rozstawione górne siekacze
• ubytek przegrody międzykomorowej
• przepuklina pępowinowa
• zaparcia
• refluks żołądkowo-przełykowy
• wygładzona moszna
• mikropenis
• spodziectwo
• wnętrostwo
• agenezja nerki
• wodonercze
• kifoskolioza
• półkręgi
• kolana koślawe
• klinodaktylia
• stopa końsko-szpotawa
• opóźnienie umysłowe
• hipotonia mięśniowa, później spastyczność
• drgawki (35%)
• atrofia mózgu
• łagodna niedokrwistość mikrocytowa hipochromiczna
• łagodna postać choroby związanej z hemoglobiną H (Hb H).
Bibliografia
• Gibbons R. Alpha thalassaemia-mental retardation, X linked. Orphanet J Rare Dis. 1, 15. 2006. doi:10.1186/1750-1172-1-15. PMID 16722615.
Linki zewnętrzne
• ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME, NONDELETION TYPE, X-LINKED; ATRX w bazie Online Mendelian Inheritance in Man (en)

 

 

Ochrona Prawna

piecz_prewencyjna_koksztys.jpg

Zjazdy i seminaria

Zespoły